Thanks for the reply Samsara.
I've enabled input display, and i've found something strange. When i press "Start" it press "Start" and "Up" both at the same time. I tried playing different games, and Super Mario Bros 1 and i can't "Start" to start the game.
However, i don't understand, because the input has been configured perfectly. I even tried again with "Clear" button, and re-enter the "Start" button only, and same problem. In comparison, my "Select" button is "JS 0 button 8" and work fine, while my "Start" button is "JS 0 button 9" and have this bug.
Maybe fceux have a problem with the Logitech Gamepad F310
But i wonder how i could fix it, i wonder if there's something i can change into the .CFG file.
Edit: I think fceux have problem with this model of controller, because i changed the input for "Start" with a letter of my keyboard, and it was working fine with that key, but as soon as i switch back to use the "Start" button from my gamepad, it do both "Start + Up". However, the gamepad itself is not the problem because it works fine with other emulator such as fce Ultra. So, for some reason, fceux 2.2.2 is unable to take only "Start" from the gamepad F310. Hmm, maybe i should try with a previous version of fceux to see if i have the same problem.
Edit2: Sorry for all these "Edit" in my message, but i just tried with the version 2.2.1 of fceux and the problem has been solved. So that confirm the version 2.2.2 of fceux have a problem with the Start button of the model of controller F310 from Logitech.