Well, this category took me time to "guess" a best run.
[3850] GB Castlevania II: Belmont's Revenge by scrimpeh in 24:41.18 - I like seeing Castlevania TASes, but this time, I saw a Castlevania game which has good action, great tricks, but has slower pace. Fortunately I liked this game!
[3849] GB Mega Man II by Tremane & Noxxa in 16:58.79 - This second GB Mega Man game...which most layouts resembles the NES titles rather than fully reimagine the original stages, has bad sound...it's a really bad game at all? No, because I don't mind about it! Not best than the latter games, but I found more entertaining than the first game. Personally this is my better choice for a trophy.
[3664] GBC Pokémon: Yellow Version by TiKevin83 in 1:36:41.68 - Well, I'm not much a Pokémon fan, but it's a good game for watch! I previously watched this game from the acclaimed ACE run by MrWint, which gave me some interest. Personally I found more interesting to see this game beating normally since I'm not very familiar. The battles are well executed too - also involves heavy luck manipulation for critical hits and avoiding enemy attacks!