My reasons for using Bizhawk are related to some of the plugins made for it, and the generally wide range of console compatibility in a single program.
For casual players that actually have a benefit from using Bizhawk, this'll be a very noticeable issue that may turn them away from using the emulator.
I understand where you're coming from with the whole TAS vs. casual player aspect, whhere Bizhawk is more meant for TASes, but at least in my mind, casual play should also be facilitated.
I've also noticed, clicking *anywhere* in bizhawk, including the settings menu and window title will trigger a tap on the DS screen (not sure where, but it registers as one, since it boots me out of the mario kart DS pre-game showcase)
I feel like in the port to bizhawk, there's no longer proper scaling like you could get on the OpenGL renderer in MelonDS. This makes games more pixelated, which isn't a bad thing per se, but can be a bother to some, including myself.