I posted a test of this in the Genesis thread here on the forums about a year ago, it seems you haven't seen it. You can find it in this thread
http://tasvideos.org/forum/viewtopic.php?t=3717.
I've only watched the first world so far and I can say it looks fairly unoptimized.
Starting with 1-2, you can punch some of the crabs just before landing on the platforms to save some damage so that you can just boost past the fish later on. You take the time to throw a bomb at one of the crabs which slows you down. And then you have to wait on the fish because you took so much damage already. You can skip waiting on the fish by punching the crabs like I said. You've lost like 85 frames alone from this from my test, but I don't know how much emulator difference is a factor if any.
In 1-3, you stop randomly for no reason and then you run into the side of walls in some locations. Also, your avoidance of the falling blocks is slow, you should be jumping earlier to go over them. By doing that, you dont have to stop to kill the seahorse guy to the left at the beginning (if you even have to at all). Also, near the end you strike your fist several times in the air after the enemy has been killed, which looks clumsy in my opinion.
In 1-5, you choose obelix again though I think I recall him being overall slower than asterix and should be avoided at all costs unless his larger hit box allows him to save time like in 1-4. Also your turn-arounds are slow, you can turn around much quicker by jumping. You waste time by throwing a bomb at the guy through the ground, when you can just punch him after you jump up.
In 1-6 I'm confused why you took damage from the dog, when it's easily avoidable with the potion ability.
In 1-7, you have several slow downs to avoid damage because you took unnecessary damage in the previous stage. Also there is a cloud glitch that you can use in this stage to save time. I used an old version of it in my test linked above, but you can actually use it as soon as you get the cloud and just climb through the ceiling there. That will allow you to skip going back to get the first key entirely which I didn't do either at the time. Your jumping with the movement speed booster item is suboptimal too, you walk forward sometimes for no reason before turning around. You also go out of your way to grab the floating powerup, which isnt even necessary to beat the level and is completely out of the way.
There are various other speed issues that I noticed too, and overall it is about 5298 frames slower in the first world alone than my test I posted above. I'm not trying to deter you from the game, it's just I like this game and I would want to see it done well and there are so many missed opportunities here. Sorry, I'll have to vote no, but I will suggest watching and improving upon my run as I'm sure it can still be improved quite a bit, but you will learn some tricks you probably didn't know.