This TAS is highly unoptimized. I can already tell from the first 10 minutes.
There is no manipulation of enemy HP tables or Stun tables; the basketball court knockback wasn't done with a downward shot (or in one shot). Aiming downward saves a couple of frames before firing, every time you draw the weapon. He also does not make any attempt to dodge the zombie in the 2F main hall of the police station.
https://www.youtube.com/watch?v=EWAZI-zogN8
https://www.youtube.com/watch?v=W6IbM50bmLg
The runs should be done on the Japanese version, since the Japanese version has more optimal enemy patterns.
If someone who is fluent in Japanese could talk to Jikkachan and Yodoru about submitting their input files (Jikkachan can be reached on YouTube, he checks his comments, but I have never spoken to Yodaru), then these are the ones that should be accepted.
As for what to do about "B" scenario files, I can tell you that the RE2 community creates "setup files" for the B scenarios. You are required to use the cable on the East side of the police station, and required to leave Marvin alive for the optimal setup file. Obviously, dirty S-RAM, but I think an exception should be made for Biohazard 2. Japanese and American players do it anyway since it requires you to make a save file to play them.