Resident Evil is the original survival horror game by Capcom, inspired by earlier works such as Alone in the Dark and Sweet Home. The Raccoon Police Department's Special Tactics And Rescue Service (S.T.A.R.S.) are assigned to investigate a series of bizarre murders on the outskirts of Raccoon City.

This run involves Jill Valentine's story through the Spencer Mansion, and aims to achieve the best ending where both Barry and Chris are saved.