It's a quiet day at the Mikami Ghost Sweeping Company until a mysterious package arrives. It seems the kindly old storekeeper Yakuchin found a magic statue and figured it would best be kept in Mikami's hands. Of course, where there's magic, there's wealth (or something like that), so Reiko sets out to find the seven gems needed to complete the statue.

GS Mikami: Joreishi wa Nice Body (GS美神 ～除霊師はナイスバディ～) is a side scrolling platform game based on the Ghost Sweeper Mikami manga and anime. The player controls Reiko who can fight off ghosts and monsters with her enchanted baton. The baton can be powered up to shoot lighting or icicles at an angle, but its power is lost if Reiko is hit. Reiko can only hold up to three special weapons, either a scroll that sucks enemies into it, or a gem that freezes time. Each case in the game is either one or two platforming levels long followed by a boss fight.