In Claymates, Clayton's father has developed a formula that can manipulate clay into animals. After he refuses to give the formula to a witch doctor, the witch takes off with the formula and Clayton's father and turns Clayton into a lump of clay. Despite his sorry condition, Clayton vows to save his father and embarks on a journey to defeat the witch.

Most of the gameplay consists of bouncing around the stages and transforming into different animals using bits of formula scattered throughout the level. Special abilities are also available that can change Clayton into animals that can take out enemies easier. Between stages, there is a mini-game where robots can be used to clear obstacles.

In this run, quietkane uses strategies such as taking damage and limiting the number of gems collected to save time on the end-level gem tally screen in order to finish this game as fast as possible.