It does indeed make more sense, but sadly it won't be possible. The time gained will be lost later, because of not being able to use Disc Armor on a Werewolf. I'm very certain Bone Pillar won't make it out of the Study without reaching 0 mana. Well... you cannot use Bone Pillar under 2 mana, so I guess that is impossible, but that doesn't really change my point.
Regardless, I'm going to use Bone Pillar against Great Armor though, the fight turns out nearly 53 frames faster, which has his soul drop nearly 200 frames earlier... no doubt very much worth the 5 frame delay it takes to change to Catoblepas.
Also, I finally found a good tactic against Graham. I had the idea a while ago, but I never got around to test it. Not really sure how much faster the fight is, around 700-800 frames I guess. Hopefully I'll be able to oneround his first phase on normal, due to the difference in attack power (This is played from my 100%).
Here is the fight:
Pie
Here is the current WIP:
More Pie
The Minotaur was a bit scrooge, it dropped my like 200 Battle Axes but never any soul. Luckily, I found a good solution. By throwing a spear at the Catoblepas it backs up and avoids turning around (it doesn't change RNG at all when it is turning around). This saved me nearly 40 frames on the Minotaur soul, which was really nice.
The first Catoblepas has 0 delay, which is awesome. It was pretty easy though, given that I could delay the Arachnes without losing time.