Not to revive a dead topic, but...
Several months ago I finished a run on this on hard. This is my first (and to date, only) TAS that I have seen through to completion. I didn't think it was quite good enough for submission for a few various reasons, such as the unoptimization of the Simon Greedwell fight (I went back and redid it about 260 frames faster, but couldn't splice that in because enemies started firing on different frames later on), not using 2 players, a couple of missed shots that I was too lazy to edit out, etc.
A few notes regarding things which have been discussed in this thread:
-Bullets do 1 damage each, regardless of player. I tested this with at least the first 3 characters, I can't remember if I tested it with Cormano.
-Bosses and objects guarding bosses receive no more than 1 damage per frame, regardless of how many bullets hit on that frame. I haven't tested it too extensively, but it seems this may actually be capped at 1 damage every other frame (i.e. if bullets hit on 2 consecutive frames, only the first actually does damage). This indicates that a 2 player run would actually provide little room for optimization over a 1 player run, except perhaps against the twins.
-I think there was something else but I can't remember it right now.
Anyway, I'd like to get some feedback on this, I've sorta been considering rerunning it recently using 2 players. I'd also like some tips on making a 2 player run, like if there's some way to record P1 for a short bit and then go back and record P2 separately. My keyboard really doesn't like me holding down enough keys simultaneously to do too much recording both at the same time.
Anyway,
here it is.